Singer and actress Kelly Osbourne, who helped Winehouse check into a drug addiction treatment facility in 2008, was one of many who grieved for the singer on Twitter.
Winehouse's health often appeared fragile. In June 2008 and again in April 2010, she was taken to hospital and treated for injuries after fainting and falling at home.
Her father said she had developed the lung disease emphysema from smoking cigarettes and crack, although her spokeswoman later said Winehouse only had "early signs of what could lead to emphysema."
She left the hospital to perform at Nelson Mandela's 90th birthday concert in Hyde Park in June 2008, and at the Glastonbury festival the next day, where she received a rousing reception but scuffled with a member of the crowd. Then it was back to a London clinic for treatment, continuing the cycle of music, excess and recuperation that marked her career.
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